P3D Bone

Available Soon

A Patient Specific and Resorbable Bone Graft Substitute

The P3D Bone is a synthetic ß-TCP bone graft substitute with bone-like porosity. The chemical composition and porous structure of the scaffold demonstrates favorable biocompatibility, osteoconduction with a rapid formation of new vascularized bone and a simultaneous and balanced biodegradability (1).

Facilitating ideal conditions for a more effective bone regeneration
We 3D print the β-TCP structures with internal porosities to maximize the surface area onto which bone cells can attach; this mimics the trabecular bone structure observed in human bones and induces the bone regeneration process.

Tricalcium Phosphate: The Optimal Synthetic Choice

Beta tricalcium phosphate (β-TCP) is the gold standard within synthetic bone graft materials (2). It is biodegradable and biocompatible and has been widely used clinically for filling and reconstructing bony defects in orthopedic surgery and dentistry.

β-TCP is the major mineral of the intercellular composite of human bones; this is why we want to rebuild them using β-TCP as this mineral contains only phosphate and calcium.

The material has the potential to optimize and surpass the natural osteoconductive and osteoinductive qualities of autogenous grafts, thereby reducing complications such as infections, bleeding and rejections (3).

Intended Use Case of P3D Bone PSI

Step 1

CT Scan

The hospital or clinic performs a CT scan of the patient.

Step 2

3D Modeling

Based on the scan, Particle3D 3D models the implant using a software tool.

Step 3

Implant Design

The surgeon accepts an implant design, and this is sent to a conveniently located Particle3D Hub.

Step 4

P3D Hub

The hub prints, sterilizes and freights the implant to the hospital or clinic.

Step 5


The hospital or clinic receives the implant within 1-2 weeks and performs the surgery.

Effective Bone Reconstruction and 3D Bone Regeneration

Favorable material composition, internal porous structure and effective individualization

The porous structure with internal voids of the P3D Bone results in a strong ingrowth of new bone. Meanwhile, the material composition provides the ideal conditions for a controlled biodegradability. This combination of bone ingrowth and simultaneous biodegradability ensures an effective remodeling of the implant into new vascularized bone (4), thereby inducing fast recovery.

The 3D printing technology also enables the manufacturing of individualized implants, which therefore require no manual adjustment in the operating room and eliminate the need to harvest bone. Surgeons can provide a P3D Bone that precisely matches patient needs, thereby increasing procedural efficiency and reduces the risk of adverse effects.

(1) Jensen, M. B., Slots, C., Ditzel, N., Albrektsen, O., Borg, S., Thygesen, T., … & Andersen, M. Ø. (2018). Composites of fatty acids and ceramic powders are versatile biomaterials for personalized implants and controlled release of pharmaceuticals. Bioprinting, 10, e00027.

(2) Fernandez de Grado G, Keller L, Idoux-Gillet Y, Wagner Q, Musset AM, Benkirane-Jessel N, et al. Bone substitutes: a review of their characteristics, clinical use, and perspectives for large bone defects management. J Tissue Eng. 2018;9:2041731418776819.

(3) St, T. J., Vaccaro, A. R., Sah, A. P., Schaefer, M., Berta, S. C., Albert, T., & Hilibrand, A. (2003). Physical and monetary costs associated with autogenous bone graft harvesting. American journal of orthopedics (Belle Mead, NJ), 32(1), 18-23.

(4) Zhang, B., Sun, H., Wu, L., Ma, L., Xing, F., Kong, Q., … & Zhang, X. (2019). 3D printing of calcium phosphate bioceramic with tailored biodegradation rate for skull bone tissue reconstruction. Bio-Design and Manufacturing, 2(3), 161-171.